Efficacy of Fine Needle Aspiration and Cytology in Solitary Thyroid Nodule

Objective: To determine the efficacy of fine needle aspiration and cytology (FNAC) in solitary thyroid nodules at tertiary care Hospital.
 Materials Methods: This study was conducted department general surgery Liaquat University Hospital Jamshoro/ Hyderabad during one year from June 2015 May 2016. The included all subjects any gender age who had a nodule that confirmed clinically or through scan. achieve tissue diagnosis before surgery, participants experienced (FNAC). resected specimens were submitted for histopathology investigation postoperatively. Diagnostic accuracy FNAC assessed by cross tabulation taking as gold standard. data gathered using self-made proforma analyzed with SPSS version 20.
 Results: Total fifty (STN) patients studied. Mean 34.54+10.3 years. Of 50 patients, 46(92%) & 4(8%) females males respectively male female ratio 1:11.5. 28(56%) STN on right lobe, left side 19(38%) cases; isthmus 3 (6%) cases. As per results, nodular colloid goiters seen 66% cases, follicular neoplasm 10%, papillary carcinoma Hurthle cell variation 6%, benign cystic lesion 4% neoplastic only 1 case, also subject suspected malignancy. Thyroid function tests normal patients. showed significant 83.3% sensitivity, 86.8% specificity, 86% diagnostic accuracy, 66.6% PPV 94.28% NPV when taken standard.
 Conclusion: In conclusion this observed to be simple, safe effective tool detecting malignancies sensitivity specificity respectively.